GeneSight
Genetic Gene Testing
Our New York Nurse Practitioners utilize GeneSight Psychotropic is a pharmacogenomic test which means that it analyzes how your genes may affect medication outcomes. The GeneSight test analyzes clinically important genetic variations in your DNA. Results can inform your doctor about how you may break down or respond to certain medications commonly prescribed to treat depression, anxiety, ADHD, and Mental Health Services NYC . The GeneSight test must be ordered by your nurse practitioner.
Understanding the GeneSight test algorithm
The GeneSight test uses a unique combinatorial algorithm, which evaluates how variations in multiple genes may influence an individual’s outcomes with certain medications.
The algorithm provides important information regarding how an individual may metabolize and/or respond to certain medications commonly prescribed to treat depression, anxiety, ADHD and other psychiatric conditions. This information supplements a healthcare provider’s comprehensive medical evaluation to help personalize treatment plans.
The GeneSight Psychotropic test has been evaluated in multiple published, peer-reviewed clinical studies. It is the only neuropsychiatric pharmacogenomic test backed by such extensive research.
The role of genetics in predicting outcomes with medications used for psychiatric conditions
Understanding the combinatorial approach of the GeneSight test starts with understanding our basic genetics: Each individual has a unique collection of genes responsible for their various genetic traits.
The GeneSight test analyzes genetic variation found in 14 total genes that may impact a patient’s outcomes with certain medications. This includes 9 pharmacokinetic genes and 5 pharmacodynamic genes:
- Pharmacokinetic (PK) genes are involved in how the body metabolizes, or breaks down, a particular medication through specific drug metabolizing enzymes.
- Pharmacodynamic (PD) genes provide information on how your DNA may impact your likelihood of response or risk for side effects with some medications.
The GeneSight test takes into consideration all clinically relevant genes known to affect metabolism or response to a medication and assigns weights based on how big (or small) of a role it is expected to play in the medication’s overall metabolism or mechanism of action.
The Bass Wellness Center of New York with Board Certified Nurse Practitioners in Psychiatry. Providing all NYC mental health services, holistic medicine, Psychotherapy and Telehealth Psychiatric Practice.
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